Publications

Yan W, Demiral ŞB, Tomasi D, Zhang R, Manza P, Wang GJ, Volkow ND. Methylphenidate promotes a frontoparietal-dominant brain state improving cognitive performance: a randomized trial. J Neurosci. 2025 Mar 18;. doi: 10.1523/JNEUROSCI.1693-24.2025. [Epub ahead of print] PubMed PMID: 40101961.

 Zhang R, Manza P, Demiral SB, Tomasi D, Yonga MV, Yan W, Shokri-Kojori E, Schwandt M, Vines L, Sotelo D, Lildharrie C, Lin E, Giddens NT, Wang GJ, Volkow ND. Rest-Activity Rhythms, Their Modulators, and Brain-Clinical Correlates in Opioid Use Disorder. JAMA Netw Open. 2025 Feb 3;8(2):e2457976. doi: 10.1001/jamanetworkopen.2024.57976. PubMed PMID: 39903462.

 Zhang R, Demiral SB, Tomasi D, Yan W, Manza P, Wang GJ, Volkow ND. Sleep Deprivation Effects on Brain State Dynamics Are Associated With Dopamine D(2) Receptor Availability Via Network Control Theory. Biol Psychiatry. 2025 Jan 1;97(1):89-96. doi: 10.1016/j.biopsych.2024.08.001. Epub 2024 Aug 8. PubMed PMID: 39127232; PubMed Central PMCID: PMC11608148.

 Zhang R, Schwandt ML, Vines L, Volkow ND. Changes in Rest-Activity Rhythms in Adolescents as They Age: Associations With Brain and Behavioral Changes in the ABCD Study. J Am Acad Child Adolesc Psychiatry. 2024 Nov 11;. doi: 10.1016/j.jaac.2024.11.005. [Epub ahead of print] PubMed PMID: 39537024.

 Zhang R, Tomasi D, Shokri-Kojori E, Manza P, Demiral SB, Wang GJ, Volkow ND. Seasonality in regional brain glucose metabolism. Psychol Med. 2024 Jul;54(9):2264-2272. doi: 10.1017/S0033291724000436. Epub 2024 Apr 18. PubMed PMID: 38634486.

 Zhang R, Yan W, Manza P, Shokri-Kojori E, Demiral SB, Schwandt M, Vines L, Sotelo D, Tomasi D, Giddens NT, Wang GJ, Diazgranados N, Momenan R, Volkow ND. Disrupted brain state dynamics in opioid and alcohol use disorder: attenuation by nicotine use. Neuropsychopharmacology. 2024 Apr;49(5):876-884. doi: 10.1038/s41386-023-01750-w. Epub 2023 Nov 7. PubMed PMID: 37935861; PubMed Central PMCID: PMC10948795.

 Agarwal K, Joseph PV, Zhang R, Schwandt ML, Ramchandani VA, Diazgranados N, Goldman D, Momenan R. Early life stress and body-mass-index modulate brain connectivity in alcohol use disorder. Transl Psychiatry. 2024 Jan 20;14(1):43. doi: 10.1038/s41398-024-02756-8. PubMed PMID: 38245501; PubMed Central PMCID: PMC10799859.

 Tomasi D, Manza P, Yan W, Shokri-Kojori E, Demiral ŞB, Yonga MV, McPherson K, Biesecker C, Dennis E, Johnson A, Zhang R, Wang GJ, Volkow ND. Examining the role of dopamine in methylphenidate's effects on resting brain function. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2314596120. doi: 10.1073/pnas.2314596120. Epub 2023 Dec 18. PubMed PMID: 38109535; PubMed Central PMCID: PMC10756194.

 Manza P, Tomasi D, Shokri-Kojori E, Zhang R, Kroll D, Feldman D, McPherson K, Biesecker C, Dennis E, Johnson A, Yuan K, Wang WT, Yonga MV, Wang GJ, Volkow ND. Neural circuit selective for fast but not slow dopamine increases in drug reward. Nat Commun. 2023 Nov 8;14(1):6408. doi: 10.1038/s41467-023-41972-6. PubMed PMID: 37938560; PubMed Central PMCID: PMC10632365.

 Zhang R, Shokri-Kojori E, Volkow ND. Seasonal effect-an overlooked factor in neuroimaging research. Transl Psychiatry. 2023 Jul 3;13(1):238. doi: 10.1038/s41398-023-02530-2. PubMed PMID: 37400428; PubMed Central PMCID: PMC10318079.

Zhang R, Volkow ND. Seasonality of brain function: role in psychiatric disorders. Transl Psychiatry. 2023 Feb 22;13(1):65. doi: 10.1038/s41398-023-02365-x. Review. PubMed PMID: 36813773; PubMed Central PMCID: PMC9947162.

Manza P, Shokri-Kojori E, Demiral ŞB, Zhang R, Dennis E, Johnson A, Vines L, Sotelo D, Tomasi D, Wang GJ, Volkow ND. Age-related differences in striatal dopamine D1 receptors mediate subjective drug effects. J Clin Invest. 2023 Jan 3;133(1). doi: 10.1172/JCI164799. PubMed PMID: 36355433; PubMed Central PMCID: PMC9797329.

Li X, Shi Z, Byanyima J, Morgan PT, van der Veen JW, Zhang R, Deneke E, Wang GJ, Volkow ND, Wiers CE. Brain glutamate and sleep efficiency associations following a ketogenic diet intervention in individuals with Alcohol Use Disorder. Drug Alcohol Depend Rep. 2022 Dec;5. doi: 10.1016/j.dadr.2022.100092. Epub 2022 Sep 8. PubMed PMID: 36311277; PubMed Central PMCID: PMC9601174.

Zhang R, Tomasi D, Shokri-Kojori E, Manza P, Feldman DE, Kroll DS, Biesecker CL, McPherson KL, Schwandt M, Wang GJ, Wiers CE, Volkow ND. Effect of detoxification on N3 sleep correlates with brain functional but not structural changes in alcohol use disorder. Drug Alcohol Depend. 2022 Sep 1;238:109545. doi: 10.1016/j.drugalcdep.2022.109545. Epub 2022 Jun 26. PubMed PMID: 35779511; PubMed Central PMCID: PMC9444901.

Manza P, Shokri-Kojori E, Demiral ŞB, Wiers CE, Zhang R, Giddens N, McPherson K, Biesecker E, Dennis E, Johnson A, Tomasi D, Wang GJ, Volkow ND. Cortical D1 and D2 dopamine receptor availability modulate methylphenidate-induced changes in brain activity and functional connectivity. Commun Biol. 2022 May 30;5(1):514. doi: 10.1038/s42003-022-03434-5. PubMed PMID: 35637272; PubMed Central PMCID: PMC9151821.

Zhang R, Wiers CE, Manza P, Tomasi D, Shokri-Kojori E, Kerich M, Almira E, Schwandt M, Diazgranados N, Momenan R, Volkow ND. Severity of alcohol use disorder influences sex differences in sleep, mood, and brain functional connectivity impairments. Brain Commun. 2022;4(4):fcac127. doi: 10.1093/braincomms/fcac127. eCollection 2022. PubMed PMID: 35794873; PubMed Central PMCID: PMC9251604.

Zhang R, Manza P, Volkow ND. Prenatal caffeine exposure: association with neurodevelopmental outcomes in 9- to 11-year-old children. J Child Psychol Psychiatry. 2022 May;63(5):563-578. doi: 10.1111/jcpp.13495. Epub 2021 Jul 27. PubMed PMID: 34318489; PubMed Central PMCID: PMC9291501.

Zhang R, Manza P, Tomasi D, Kim SW, Shokri-Kojori E, Demiral SB, Kroll DS, Feldman DE, McPherson KL, Biesecker CL, Wang GJ, Volkow ND. Dopamine D1 and D2 receptors are distinctly associated with rest-activity rhythms and drug reward. J Clin Invest. 2021 Sep 15;131(18). doi: 10.1172/JCI149722. PubMed PMID: 34264865; PubMed Central PMCID: PMC8439593.

Zhang R, Tomasi D, Manza P, Shokri-Kojori E, Demiral SB, Feldman DE, Kroll DS, Biesecker CL, McPherson KL, Wang GJ, Wiers CE, Volkow ND. Sleep disturbances are associated with cortical and subcortical atrophy in alcohol use disorder. Transl Psychiatry. 2021 Aug 16;11(1):428. doi: 10.1038/s41398-021-01534-0. PubMed PMID: 34400604; PubMed Central PMCID: PMC8368207.

Tomasi D, Wiers CE, Manza P, Shokri-Kojori E, Michele-Vera Y, Zhang R, Kroll D, Feldman D, McPherson K, Biesecker C, Schwandt M, Diazgranados N, Koob GF, Wang GJ, Volkow ND. Accelerated Aging of the Amygdala in Alcohol Use Disorders: Relevance to the Dark Side of Addiction. Cereb Cortex. 2021 Jun 10;31(7):3254-3265. doi: 10.1093/cercor/bhab006. PubMed PMID: 33629726; PubMed Central PMCID: PMC8196255.

Wiers CE, Vendruscolo LF, van der Veen JW, Manza P, Shokri-Kojori E, Kroll DS, Feldman DE, McPherson KL, Biesecker CL, Zhang R, Herman K, Elvig SK, Vendruscolo JCM, Turner SA, Yang S, Schwandt M, Tomasi D, Cervenka MC, Fink-Jensen A, Benveniste H, Diazgranados N, Wang GJ, Koob GF, Volkow ND. Ketogenic diet reduces alcohol withdrawal symptoms in humans and alcohol intake in rodents. Sci Adv. 2021 Apr;7(15). doi: 10.1126/sciadv.abf6780. Print 2021 Apr. PubMed PMID: 33837086; PubMed Central PMCID: PMC8034849.

Kroll DS, Feldman DE, Wang SA, Zhang R, Manza P, Wiers CE, Volkow ND, Wang GJ. The associations of comorbid substance use disorders and psychiatric conditions with adolescent brain structure and function: A review. J Neurol Sci. 2020 Nov 15;418:117099. doi: 10.1016/j.jns.2020.117099. Epub 2020 Aug 19. Review. PubMed PMID: 32866814; PubMed Central PMCID: PMC9003866.

Zhang R, Tomasi D, Shokri-Kojori E, Wiers CE, Wang GJ, Volkow ND. Sleep inconsistency between weekends and weekdays is associated with changes in brain function during task and rest. Sleep. 2020 Oct 13;43(10). doi: 10.1093/sleep/zsaa076. PubMed PMID: 32333599; PubMed Central PMCID: PMC7551301.

Zhang R, Werner A, Hermann W, Brandt MD, Beste C, Stock AK. Thalamic GABA may modulate cognitive control in restless legs syndrome. Neurosci Lett. 2019 Nov 1;712:134494. doi: 10.1016/j.neulet.2019.134494. Epub 2019 Sep 11. PubMed PMID: 31520647.

Zhang R, Volkow ND. Brain default-mode network dysfunction in addiction. Neuroimage. 2019 Oct 15;200:313-331. doi: 10.1016/j.neuroimage.2019.06.036. Epub 2019 Jun 21. Review. PubMed PMID: 31229660.

Zink N, Zhang R*, Chmielewski WX, Beste C, Stock AK. Detrimental effects of a high-dose alcohol intoxication on sequential cognitive flexibility are attenuated by practice. Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:97-108. doi: 10.1016/j.pnpbp.2018.08.034. Epub 2018 Sep 5. PubMed PMID: 30193989. *shared first-author

Giller F, Zhang R, Roessner V, Beste C. The neurophysiological basis of developmental changes during sequential cognitive flexibility between adolescents and adults. Hum Brain Mapp. 2019 Feb 1;40(2):552-565. doi: 10.1002/hbm.24394. Epub 2018 Sep 21. PubMed PMID: 30240511; PubMed Central PMCID: PMC6865493.

Zhang R, Schrempf W, Brandt MD, Mückschel M, Beste C, Stock AK. RLS patients show better nocturnal performance in the Simon task due to diminished visuo-motor priming. Clin Neurophysiol. 2018 Jan;129(1):112-121. doi: 10.1016/j.clinph.2017.10.022. Epub 2017 Nov 6. PubMed PMID: 29172115.

Zhang R, Stock AK, Rzepus A, Beste C. Self-Regulatory Capacities Are Depleted in a Domain-Specific Manner. Front Syst Neurosci. 2017;11:70. doi: 10.3389/fnsys.2017.00070. eCollection 2017. PubMed PMID: 29033798; PubMed Central PMCID: PMC5625007.

Zhang R, Brandt MD, Schrempf W, Beste C, Stock AK. Neurophysiological mechanisms of circadian cognitive control in RLS patients - an EEG source localization study. Neuroimage Clin. 2017;15:644-652. doi: 10.1016/j.nicl.2017.06.018. eCollection 2017. PubMed PMID: 28664035; PubMed Central PMCID: PMC5480014.

Zhang R, Stock AK, Fischer R, Beste C. The system neurophysiological basis of backward inhibition. Brain Struct Funct. 2016 Dec;221(9):4575-4587. doi: 10.1007/s00429-016-1186-0. Epub 2016 Jan 23. PubMed PMID: 26803755.

Zhang R, Stock AK, Beste C. The neurophysiological basis of reward effects on backward inhibition processes. Neuroimage. 2016 Nov 15;142:163-171. doi: 10.1016/j.neuroimage.2016.05.080. Epub 2016 Jun 1. PubMed PMID: 27262242.

Beste C, Steenbergen L, Sellaro R, Grigoriadou S, Zhang R, Chmielewski W, Stock AK, Colzato L. Effects of Concomitant Stimulation of the GABAergic and Norepinephrine System on Inhibitory Control - A Study Using Transcutaneous Vagus Nerve Stimulation. Brain Stimul. 2016 Nov-Dec;9(6):811-818. doi: 10.1016/j.brs.2016.07.004. Epub 2016 Jul 19. PubMed PMID: 27522167.